Can i take tylenol and benadryl together

Tylenol Arthritis Pain Interactions. There are 114 drugs known to interact with Tylenol Arthritis Pain (acetaminophen), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 8 are major, 71 are moderate, and 35 are minor.

Can i take tylenol and benadryl together. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen, and can increase certain side effects of diphenhydramine.

1 Okt 2020 ... FDA warns against taking higher than recommended doses of over-the-counter Benadryl, which can lead to serious problems and death.

A total of 438 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis.Mar 9, 2022 · Taking too much acetaminophen can cause severe liver damage. Adult daily dosing should not exceed 3,250 mg within 24 hours, and children should not consume more than 1,625 mg within 24 hours. Do not mix this drug with other medications containing acetaminophen. Warnings. This medication contains acetaminophen/diphenhydramine/dextromethorphan. Do not take Diabetic Tussin Nighttime Cold & Flu if you are allergic to ...A total of 438 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis.Yes you can: There is no significant interaction between the two medicines and so can be taken together if needed. As a matter of fact, tylenol -pm is a combo of both of these meds. Of course, use the smallest effective dose and the shortest duration whenever possible. If symptoms persist, consult doc. Good luck.15 Jan 2022 ... ... at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose.Pain Relief You Can Count On. See why the #1 doctor recommended brand of pain reliever may be right for you. Learn more about acetaminophen safety and recommended adult dosages, as well as our full line of TYLENOL® products.

If neither is the case, "it should be relatively safe to take cold and allergy medication together as long as you're following the dosing instructions on the package," says Dr. Patel. Common cold ...Paxlovid disease interactions. There are 7 disease interactions with Paxlovid (nirmatrelvir / ritonavir) which include: liver dysfunction. renal dysfunction. hemophilia. hyperglycemia. hyperlipidemia. heart block. hepatotoxicity.Oct 1, 2023 · Vicodin HP. Zydone. Descriptions. Hydrocodone and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. Oct 12, 2023 · If you are pregnant, it is generally safe to take a regular Tylenol dosage of two tablets or capsules of 325 milligrams (mg) each every four to six hours. Do not take more …Drug Interactions between Benadryl and Tylenol. This report displays the potential drug interactions for the following 2 drugs: Benadryl (diphenhydramine) Tylenol (acetaminophen) Edit list (add/remove drugs) Interactions between your drugsYes you can: There is no significant interaction between the two medicines and so can be taken together if needed. As a matter of fact, tylenol -pm is a combo of both of these meds. Of course, use the smallest effective dose and the shortest duration whenever possible. If symptoms persist, consult doc. Good luck.Applies to: Tylenol Cold & Flu Severe (acetaminophen / dextromethorphan / guaifenesin / phenylephrine) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience ...Can You Overdose on Both Drugs? Alternatives to Benadryl; Talk to Your Doctor; Sources. Benadryl is an over the counter allergy medication. It can cause some ...

A total of 438 drugs are known to interact with Benadryl . Benadryl is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis.Oct 1, 2023 · Antihistamine and decongestant combinations are used to treat the nasal congestion (stuffy nose), sneezing, and runny nose caused by colds and hay fever. Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Benadryl (diphenhydramine) CoQ10 (ubiquinone) Cymbalta (duloxetine) ... Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) ... assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available.TYLENOL Rapid Release Gels for Fast Pain, Headache & Fever Relief for Adults, 500mg Acetaminophen. BUY NOW. ★★★★★ ★★★★★. 4.6. Oct 6, 2023 · Dr. Charles Glassman answered. Internal Medicine 38 years experience. Tylenol (acetaminophen) PM: Tylenol (acetaminophen) pm is tylenol (acetaminophen) …

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If you need to take a buffered form of this medicine, and you are also taking one of the following medicines, be sure to take the buffered acetaminophen and salicylate combination medicine: At least 6 hours before or 2 hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin (e.g., Maxaquin). At least 8 hours before or 2 hours after ...If you need to take a buffered form of this medicine, and you are also taking one of the following medicines, be sure to take the buffered acetaminophen and salicylate combination medicine: At least 6 hours before or 2 hours after taking ciprofloxacin (e.g., Cipro) or lomefloxacin (e.g., Maxaquin). At least 8 hours before or 2 hours after ...Feb 9, 2011 · Don't take any more PMs with the tylenol for the benadryl tho'! Like the others said, you can buy benadryl (diphenhydramine HCI.25 mg)You may be able (addressing the sleeping problem) to just take benadryl. If you have a "Dollar General " store close by, they sell them 100 in a bottle for $4. Skip the tylenol for your livers sake; but back to ... The short answer: It depends on the drugs in question. But in the case of gabapentin and Tylenol (acetaminophen), you can take them both together. In fact, many folks do. While both...

Nov 5, 2022 · Tylenol 8-Hour Aches and Pains ER. Tylenol 8-Hour Aches and Pains Extended-Release is basically the same as the formulation for arthritis pain. This type of Tylenol contains 650 mg acetaminophen per caplet, has the same bi-layer design, and is formulated to relieve minor muscle aches and body pain fast and to last all day. Take acetaminophen ( Tylenol) or ibuprofen ( Motrin )for pain relief as needed. Wash the sting site with soap and water. Placing hydrocortisone cream on the sting can help relieve redness, itching ...Oct 1, 2023 · The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large …Benadryl allergy is in the following drug classes: anticholinergic antiemetics, anticholinergic antiparkinson agents, antihistamines, miscellaneous anxiolytics, sedatives and hypnotics . Benadryl allergy is used to treat the following conditions: Allergic Reactions. Allergic Rhinitis. Cold Symptoms. Cough. Extrapyramidal Reaction. Motion Sickness.Acetaminophen comes as a tablet, chewable tablet, capsule, suspension or solution (liquid), extended-release (long-acting) tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth), to take by mouth, with or without food. Acetaminophen is available without a prescription, but your doctor may prescribe acetaminophen ... Paxlovid disease interactions. There are 7 disease interactions with Paxlovid (nirmatrelvir / ritonavir) which include: liver dysfunction. renal dysfunction. hemophilia. hyperglycemia. hyperlipidemia. heart block. hepatotoxicity.Acetaminophen is a pain reliever and a fever reducer. Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy ...The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence ...Aug 9, 2022 · There are many possible interactions with diphenhydramine. Below, we’ll go over some common ones to watch out for. Keep in mind that this isn’t a complete list. For your safety, always ask your pharmacist or healthcare provider about possible interactions. The same goes for after a shot: “If you don’t need to take it, you shouldn’t,” Watanabe said. If you do need one, acetaminophen (Tylenol) “is safer because it doesn’t alter your immune ...Aug 4, 2023 · 6. Alcohol. Alcohol and Benadryl have sedative functions, so you can experience adverse effects when taken together or within the same time frame. Combining alcohol and Benadryl can lead to drowsiness, dizziness, difficulty concentrating, poor motor skills, and an increased risk of drug overdose. Mar 12, 2022 · Yes, Benadryl ( diphenhydramine) may be safely taken with Tylenol ( acetaminophen) as there is no drug interaction between the two. In fact, these two drugs can often be found together in the same product.

6 Nov 2017 ... ... Tylenol, Advil, and Benadryl dosage for children. These dosage charts will give your child the right amount of medicine to help them feel ...

Benadryl (diphenhydramine) Claritin (loratadine) CoQ10 (ubiquinone) Cymbalta (duloxetine) ... Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) ... assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information ...Apr 16, 2023 · However, there are some exceptions: A healthcare provider may sometimes recommend a combination of both Tylenol (acetaminophen) and Motrin (ibuprofen). Some evidence suggests prolonged use of Tylenol and Motrin together may increase the risk of upper gastrointestinal bleeding more than Motrin alone. However, their combined use can sometimes ... 20 Jun 2018 ... Learn which common medications to avoid during treatment. Many people know that taking a sedative and an antihistamine at the same time can ...Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D2 (ergocalciferol) Vitamin D3 (cholecalciferol) Xanax (alprazolam) Xarelto (rivaroxaban) Zyrtec (cetirizine) Valsartan alcohol/food interactions. There are 2 alcohol/food interactions with valsartan. Valsartan disease interactionsSome people may need to combine different allergy medications to treat their allergy symptoms. It’s safe for most people to take allergy medications that are in different classes. For example, nasal steroids and oral decongestants can be taken together. However, you shouldn’t combine oral antihistamines, such as Zyrtec and Benadryl, without ...Acetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine. Phenylephrine is a decongestant. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body...Using diphenhydrAMINE together with HYDROcodone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these ... We would like to show you a description here but the site won't allow us.How should I take Tylenol? Take Tylenol exactly as directed on the label, or as prescribed by your doctor. An acetaminophen overdose can damage your liver or cause death. Adults and teenagers who weigh at least 110 pounds (50 kilograms): Do not take more than 1000 milligrams (mg) at one time. Do not take more than 4000 mg in 24 hours.See full list on hellopharmacist.com

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NSAID Warnings. Prednisone (sold as Rayos, Prednisone Intensol, Orapred ODT) and Advil (ibuprofen) are among the most common medications for pain and inflammation. Although they are largely safe on …Drug Interactions between Benadryl and Tylenol PM. This report displays the potential drug interactions for the following 2 drugs: Benadryl (diphenhydramine) Tylenol PM ... This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a ...Kenvue KVUE, -1.30%, the parent of a number of household consumer brands, including Tylenol, Band-Aid, Listerine and Benadryl, said late Wednesday that it sold 172.8 million shares in the IPO, up ...Benadryl (diphenhydramine) Cymbalta (duloxetine) doxycycline; Fish Oil (omega-3 polyunsaturated fatty acids) fluoxetine; gabapentin; ibuprofen; Lamictal (lamotrigine) ... Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction ...25 Mar 2021 ... Taking Tylenol PM While Pregnant ... Tylenol PM is a combination of two drugs: Acetaminophen and diphenhydramine (an antihistamine found in ...Benadryl (diphenhydramine) Colace (docusate) docusate; ... multivitamin; omeprazole; oxycodone; pantoprazole; potassium chloride; prednisone; tramadol; trazodone; Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) ... assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or ...Paracetamol (acetaminophen or para-hydroxyacetanilide) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. It is a widely used over the counter medication and common brand names include Tylenol and Panadol.. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior to ibuprofen in …Acetaminophen (Tylenol) has long been considered one of the few drugs safe to take during pregnancy, but a 2016 study in the I nternational Journal of Epidemiology found a link between acetaminophen and autism. While studies like this are scary, it doesn’t mean women shouldn’t take Tylenol.Feb 13, 2023 · The short answer: It depends on the drugs in question. But in the case of gabapentin and Tylenol (acetaminophen), you can take them both together. In fact, many folks do. While both medications ... The best way to alternate Tylenol and ibuprofen (Advil) is to take them 2 to 4 hours apart. For example, if you get up at 6.00am, you can take a dose of ibuprofen, then at 8.00am, you can take a dose of Tylenol. You can continue this regimen throughout the day, making sure you don’t exceed the recommended maximum dose for each drug.Summary. Tylenol is safe and effective for managing pain and fevers. The dose will depend on the infant’s size and weight but should not exceed four doses in 24 hours. Check with a doctor if the ...Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. ….

Do not combine with other medicines that could contain acetaminophen. Keep ... Please do not drive or operate dangerous equipment after taking diphenhydramine.Feb 13, 2023 · The short answer: It depends on the drugs in question. But in the case of gabapentin and Tylenol (acetaminophen), you can take them both together. In fact, many folks do. While both medications ... It is a combination of acetaminophen and an antihistamine. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have ...Tylenol can be dangerous if a person takes the medication incorrectly. For example, people may experience severe liver damage by:. taking more than 4,000 milligrams (mg) of Tylenol in 24 hoursAcetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine. Phenylephrine is a decongestant. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body...Oct 1, 2023 · Diphenhydramine and ibuprofen combination is used to relieve trouble sleeping caused by minor aches and pains. It also helps you fall asleep and stay asleep. …Paxlovid disease interactions. There are 7 disease interactions with Paxlovid (nirmatrelvir / ritonavir) which include: liver dysfunction. renal dysfunction. hemophilia. hyperglycemia. hyperlipidemia. heart block. hepatotoxicity.Yes: 25 mg Benadryl (diphenhydramine) is ok. Avoid Xanax in the future. It can be sedating, but highly addictive. Half life is 2-4 hrs so it's completely o... Read More. Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help. Together: Tylenol (acetaminophen) and benadryl can be taken together. They work in different ways and there are not drug interactions . Created for people with ongoing healthcare needs but benefits everyone.The same goes for after a shot: “If you don’t need to take it, you shouldn’t,” Watanabe said. If you do need one, acetaminophen (Tylenol) “is safer because it doesn’t alter your immune ... Can i take tylenol and benadryl together, Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., However, there are some exceptions: A healthcare provider may sometimes recommend a combination of both Tylenol (acetaminophen) and Motrin (ibuprofen). Some evidence suggests prolonged use of Tylenol and Motrin together may increase the risk of upper gastrointestinal bleeding more than Motrin alone. However, their combined use …, For example, Ziebarth says Tylenol PM is a combination of the ingredients in Tylenol and Benadryl. “We tell patients, yes you can take Tylenol and yes you can take Benadryl, but if you take ..., Dec 19, 2018 · Takeaway. Generally, it’s safe to take acetaminophen and ibuprofen together, but you’ll want to pay close attention to how much you take of each medication. Acetaminophen (Tylenol) and ... , Severe liver damage may occur if you take more than 4,000 mg of acetaminophen in 24 hours, with other drugs containing acetaminophen, and/or 3 or more alcoholic drinks every day while using this product. Ask a doctor before use if you have liver disease. Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include, skin ... , Clonidine can cause drowsiness, low blood pressure, and a slower heart rate. Combining it with certain medications can worsen these effects. Examples include tricyclic antidepressants, calcium channel blockers, and alcohol. Your healthcare provider can help you avoid or manage serious clonidine interactions., Acetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine. Phenylephrine is a decongestant. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body..., Oct 1, 2023 · Diphenhydramine and ibuprofen combination is used to relieve trouble sleeping caused by minor aches and pains. It also helps you fall asleep and stay asleep. …, Aug 4, 2023 · Tylenol can be taken on its own, but there are many multi-symptom cold & flu remedies that also contain acetaminophen as an active ingredient. These include: Alka-Seltzer Plus Cold & Flu. Contac Cold + Flu. Coricidin HBP Cold & Flu. Equate Cold & Flu Multi-Symptom Relief. Mucines Cold & Flu. Robitussin Multi-Symptom Cough Cold + Flu. , Antihistamine and decongestant combinations are used to treat the nasal congestion (stuffy nose), sneezing, and runny nose caused by colds and hay fever. Antihistamines work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes., Applies to: Mucinex DM (dextromethorphan / guaifenesin) and Benadryl (diphenhydramine) Using dextromethorphan together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor ..., Do not combine with other medicines that could contain acetaminophen. Keep ... Please do not drive or operate dangerous equipment after taking diphenhydramine., Jul 28, 2023 · 1. How it works. Tylenol is a brand (trade) name for acetaminophen and is used to relieve pain. Experts aren't sure exactly how acetaminophen works, but suspect it blocks a specific type of cyclo-oxygenase (COX) enzyme, located mainly in the brain. Tylenol belongs to the class of medicines called analgesics (pain relievers); it is specifically ... , In terms of specifics: acetaminophen (Tylenol), naproxen (Aleve) or ibuprofen (Advil, Motrin) can help lower your fever, assuming you don’t have a health history that should prevent you from using them. It’s usually not necessary to lower a fever – an elevated temperature is meant to help your body fight off the virus., Nov 4, 2022 · It can still be confusing to know which medications are OK to mix. For example, combining Tylenol with an antihistamine like Benadryl is safe. “Remember, every medication ingredient is doing ... , Benadryl (Diphenhydramine) received an overall rating of 7 out of 10 stars from 221 reviews. See what others have said about Benadryl (Diphenhydramine), including the effectiveness, ease of use and side effects. I took it every 4 hours for ..., Acetaminophen comes as a tablet, chewable tablet, capsule, suspension or solution (liquid), extended-release (long-acting) tablet, and orally disintegrating tablet (tablet that dissolves quickly in the mouth), to take by mouth, with or without food. Acetaminophen is available without a prescription, but your doctor may prescribe acetaminophen ... , Applies to: Tylenol with Codeine #3 (acetaminophen / codeine) and Benadryl (diphenhydramine) Using codeine together with diphenhydrAMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. , Painkiller: The Tylenol Murders. October 10, 2023. In 1982 seven people, mostly in and around Chicago, died suddenly and without explanation. The victims included three people from one family and ..., Description and Brand Names. Drug information provided by: Merative, Micromedex® US Brand Name. Lagevrio; Descriptions. Molnupiravir is used to treat mild to moderate coronavirus disease 2019 (COVID-19) in non-hospitalized patients who are at high risk for progression to severe COVID-19 (eg, hospitalization, death) or in patients for …, Yes you can: There is no significant interaction between the two medicines and so can be taken together if needed. As a matter of fact, tylenol -pm is a combo of both of these meds. Of course, use the smallest effective dose and the shortest duration whenever possible. If symptoms persist, consult doc. Good luck., You can take Claritin and Benadryl together, but the effect of both drugs overlap, according to BJC HealthCare. Both Claritin and Benadryl are antihistamines, which means that taking them together would be duplicating the active drug of eac..., Yes: Benadryl (diphenhydramine) and codeine individually can make you sleepy, so take care when using these medications together as the effect may be magni... Read More. Created for people with ongoing healthcare needs but benefits everyone., How often to give the medicine (frequency): You can give acetaminophen every 4 to 6 hours as needed. Do not give more than 4 doses in 24 hours. Oral disintegrating tablets: These are dissolvable tablets that come in 80 mg and 160 mg (junior strength) Suppositories (medicine that is put in the rectum, or butt): Acetaminophen also comes in 80 ..., Oct 1, 2023 · The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large …, Some people may need to combine different allergy medications to treat their allergy symptoms. It’s safe for most people to take allergy medications that are in different classes. For example, nasal steroids and oral decongestants can be taken together. However, you shouldn’t combine oral antihistamines, such as Zyrtec and Benadryl, …, Oct 1, 2023 · Diphenhydramine and ibuprofen combination is used to relieve trouble sleeping caused by minor aches and pains. It also helps you fall asleep and stay asleep. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used in this combination to relieve inflammation, swelling, and pain. This medicine is available as an over-the-counter ... , A person can usually take acetaminophen-based pain relievers like Tylenol more frequently. Tylenol generally comes in 325 milligram (mg), 500 mg, or 650 mg pills., According to WebMD, there are no drug interactions between Tylenol and Benadryl, so they can be taken at the same time. However, a personal doctor or pharmacist should always be informed, so they can add this information to the medication list. Tylenol is a brand name for acetaminophen, a type of over-the-counter pain reliever and fever reducer ..., Feb 8, 2023 · The best way to alternate Tylenol and ibuprofen (Advil) is to take them 2 to 4 hours apart. For example, if you get up at 6.00am, you can take a dose of ibuprofen, then at 8.00am, you can take a dose of Tylenol. You can continue this regimen throughout the day, making sure you don’t exceed the recommended maximum dose for each drug. , Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen, and can increase certain side effects of diphenhydramine., If medication is past its expiration date, discard it and replace it with new product, says the makers of Benadryl. However, many medications are safe and effective well past their expiration dates, according to The Allergy Clinic., Acetaminophen is a pain reliever and fever reducer. Diphenhydramine is an antihistamine. Phenylephrine is a decongestant. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body...